41. Health Library Rural Institute on DisabilitiesDisability Helpline. Rural Issues. russell-silversyndrome. russell-silver syndrome Support Network-russell-silver syndrome. http://hvelink.saint-lukes.org/library/healthguide/SelfHelp/_SearchResults.asp?l

42. Russell-Silver Syndrome russellsilver syndrome. russell-silver syndrome is a very rare geneticdisorder. Most cases of russell-silver syndrome are the result http://www.manbir-online.com/diseases/russell-silver.htm

Home Medi News Medical Tidbits Interesting Topics ... Manbir Mail Russell-Silver Syndrome Russell-Silver Syndrome is a very rare genetic disorder. Most cases of Russell-Silver Syndrome are the result of new genetic changes (mutations) that occur randomly for no apparent reason. A rare form of Russell-Silver Syndrome is thought to be inherited as an X-linked dominant genetic trait. The incidence of this disease is uncertain yet. Some say - The incidence are quite high, eg in the US alone 1:100 babies are born with it !!! Some features seen in this syndrome : - Growth delays, which starts before birth ( intrauterine growth retardation) Overgrowth of one side of the body (hemihypertrophy or asymmetry) Unusual characteristic facial features. Affected infants may be low birth weight. Growth delays and immature bone development continue after birth. Asymmetry or overgrowth of one side of the body is obvious at birth. Asymmetry may affect the head, trunk, arms, and/or legs.

43. Manbir Online .... Diseases & Conditions Rabies. Role of Nitric Oxide. russellsilver syndrome. Ricin. Sun Burns. Homocystinuria.russell-silver syndrome. Huntington's chorea. Osteogenesis Imperfecta. http://www.manbir-online.com/diseases.htm

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44. Russell-Silver Syndrome russellsilver syndrome. Definition Children with russell-silver syndromeare born small and generally achieve less than 5 feet at adult height. http://www.pennhealth.com/ency/article/001209.htm

Disease Injury Nutrition Poison ... Prevention Russell-Silver syndrome Definition: A condition of unknown origin, but which is characterized by short stature and frequent asymmetry in the size of 2 halves or parts of the body. Alternative Names: Silver Russell syndrome; Silver syndrome Causes, incidence, and risk factors: Genetic problems are thought to cause this syndrome although the specific gene(s) remain to be discovered. The pattern of inheritance has not been determined but in most cases it seems sporadic, that is to say, there is no family history in preceding generations/siblings. Children with Russell-Silver syndrome are born small and generally achieve less than 5 feet at adult height. Side-to-side asymmetry is fairly common, for example a left body part may be larger than the right counterpart. This asymmetry may occur anywhere including the face. Other findings include excessive sweating , a small triangular face which makes the skull look large by comparison, inward curving 5th fingers, and pigmented skin lesions called cafe-au-lait spots Review Date: 9/10/2001 Reviewed By: David G. Brooks, M.D., Ph.D., Division of Medical Genetics, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.

45. Russell-Silver Syndrome russellsilver syndrome. Alternative Names silver russell syndrome;silver syndrome. Symptoms slow growth from before birth http://www.pennhealth.com/ency/article/001209sym.htm

Disease Injury Nutrition Poison ... Prevention Russell-Silver syndrome Alternative Names: Silver Russell syndrome; Silver syndrome Symptoms: slow growth from before birth, intrauterine growth retardation short stature throughout childhood and at final height delay in closure of the soft spot on top of the head in infancy small triangular face with normal head circumference cafe-au-lait (coffee with milk) colored spots short and or in-curved 5th fingers Signs and tests: Physical examination may show: delayed closure of anterior fontanel (soft spot) side to side asymmetry (especially limbs) curved-in fifth finger (clinodactyly) normal intelligence micrognathia or retrognathia (small or "pushed-back" jaw) Tests: A glucose tolerance test may show episodes of low blood sugar hypoglycemia ) when fasting. Skeletal X-rays may show a discrepancy (delay) between "bone age" (the age that the bones appear) and the actual age or sexual development. Review Date: 9/10/2001 Reviewed By: David G. Brooks, M.D., Ph.D., Division of Medical Genetics, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.

46. Health Library: All Topics: R: Russell-Silver Syndrome - Healthfinder® home health library all topics R russellsilver syndrome. categories andrelated topics. find a specific kind of information on russell-silver syndrome http://www.healthfinder.gov/Scripts/SearchContext.asp?topic=760&refine=1

47. Health Library - Russell-Silver Syndrome Topics. russellsilver syndrome. Self Help Clearinghouse. russell-silversyndrome Support Network. National network. Founded http://uhcs.universityhealth.org/library/healthguide/selfhelp/topic.asp?hwid=shc

48. Health Library - Russell-Silver Syndrome FREE. russellsilver syndrome. Self Help Clearinghouse. russell-silversyndrome Support Network. National network. Founded http://hvlib.integris-health.com/Library/HealthGuide/SelfHelp/topic.asp?hwid=shc

49. Health Library Rural Issues. russellsilver syndrome. russell-silver syndrome SupportNetwork-russell-silver syndrome. CAREERS EVENTS HELP SITE INDEX. http://hvlib.integris-health.com/Library/HealthGuide/SelfHelp/_SearchResults.asp

50. Health Ency.: Disease: Russell-Silver Syndrome russellsilver syndrome. Children with russell-silver syndrome are bornsmall and generally achieve less than 5 feet at adult height. http://www.austin360.com/shared/health/adam/ency/article/001209.html

SEARCH: The Web Yellow Pages HOME Illustrated Health Encyclopedia Important notice Ency. home Disease R Russell-Silver syndrome Overview Symptoms Treatment Prevention Alternative names: Silver Russell syndrome; Silver syndrome Definition: A condition of unknown origin, but which is characterized by short stature and frequent asymmetry in the size of 2 halves or parts of the body. Causes and Risks Genetic problems are thought to cause this syndrome although the specific gene(s) remain to be discovered. The pattern of inheritance has not been determined but in most cases it seems sporadic, that is to say, there is no family history in preceding generations/siblings. Children with Russell-Silver syndrome are born small and generally achieve less than 5 feet at adult height. Side-to-side asymmetry is fairly common, for example a left body part may be larger than the right counterpart. This asymmetry may occur anywhere including the face. Other findings include excessive sweating , a small triangular face which makes the skull look large by comparison, inward curving 5th fingers, and pigmented skin lesions called cafe-au-lait spots Ency. home

51. Health Ency.: Disease: Russell-Silver Syndrome Ency. home Disease R russellsilver syndrome. russell-silver syndrome. Treatment.There is no specific treatment for russell-silver syndrome. http://www.austin360.com/shared/health/adam/ency/article/001209trt.html

SEARCH: The Web Yellow Pages HOME Illustrated Health Encyclopedia Important notice Ency. home Disease R Russell-Silver syndrome Overview Symptoms Treatment Prevention Alternative names: Silver Russell syndrome; Silver syndrome Treatment There is no specific treatment for Russell-Silver syndrome. Symptoms are treated as necessary. Sometimes growth hormone replacement is recommended, for example in documented growth hormone deficiency, with varying results. Supportive treatment for discrepancy of leg length may prevent problems. Prognosis As the child ages, many will improve in growth and appearance. There is normal intelligence. Complications self esteem and emotional problems related to appearance chewing or speaking difficulty if jaw is very small there may be an increased risk for tumors of the liver Call Your Health Care Provider If: There may be some indications of this condition at birth. Call your health care provider if your child does not seem to be growing normally and has asymmetry of body parts or in-turned 5th fingers. Ency. home

52. Russell-Silver Syndrome - General Practice Notebook russellsilver syndrome. russell-silver syndrome is an inherited causeof short stature and a number of other characteristic features. http://www.gpnotebook.co.uk/cache/-603586547.htm

Russell-Silver syndrome Russell-Silver syndrome is an inherited cause of short stature and a number of other characteristic features. After a provocation test there is a surge in growth hormone; there is an initial response to growth hormone treatment which may not be maintained. There is an association with Wilm's tumour. Click here for more information...

53. EMedicine - Silver-Russell Syndrome : Article By Ainu Prakash-Cheng, MD, PhD Synonyms and related keywords SRS, russellsilver syndrome, silver-russell dwarfism,silver syndrome. Vol. I. 1997 737-752. Jones KL russell-silver syndrome. http://www.emedicine.com/PED/topic2099.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Pediatrics Genetics And Metabolic Disease Silver-Russell Syndrome Last Updated: February 14, 2002 Rate this Article Email to a Colleague Synonyms and related keywords: SRS, Russell-Silver syndrome, Silver-Russell dwarfism, Silver syndrome AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Ainu Prakash-Cheng, MD, PhD , Assistant Professor of Human Genetics and Pediatrics, Department of Human Genetics, Mount Sinai School of Medicine Coauthor(s): Margaret McGovern, MD, PhD , Vice Chair, Associate Professor, Department of Human Genetics, Mount Sinai School of Medicine Ainu Prakash-Cheng, MD, PhD, is a member of the following medical societies: American Academy of Pediatrics American Society of Gene Therapy , and American Society of Human Genetics Editor(s): Elaine H Zackai, MD , Director of Clinical Genetics Center, Professor of Pediatrics, Department of Pediatrics, Division of Human Genetics and Molecular Biology, University of Pennsylvania, Children's Hospital of Philadelphia;

54. EMedicine - Silver-Russell Syndrome : Article Excerpt By: Ainu Prakash-Cheng, MD Excerpt from silverrussell syndrome. Synonyms, Key Words, and Related TermsSRS, russell-silver syndrome, silver-russell dwarfism, silver syndrome. http://www.emedicine.com/ped/byname/silver-russell-syndrome.htm

(advertisement) Excerpt from Silver-Russell Syndrome Synonyms, Key Words, and Related Terms: SRS, Russell-Silver syndrome, Silver-Russell dwarfism, Silver syndrome Please click here to view the full topic text: Silver-Russell Syndrome Background: Silver-Russell syndrome (SRS) originally was described by Silver and colleagues in 1953 and, soon afterwards, by Russell in 1954. The first reports were of children with characteristic facies, low birthweight, asymmetry, and growth retardation. Over the past several years, more than 400 patients have been described, with phenotypes ranging from mild to classic. Some patients have maternal uniparental disomy of chromosome 7, with the possibility of imprinting (eg, inheriting 2 copies of maternal chromosome 7, with no paternal contribution). Pathophysiology: Growth failure is the primary abnormality. Patients present with intrauterine growth retardation, difficulty feeding, failure to thrive, or postnatal growth retardation that may be caused by immature osseous development through early childhood. Although catch-up growth often occurs during adolescence, the final height still is less than normal ( -3.6 SD). Older children and adults do not manifest clinical features as clearly as infants or young children.

55. Russell – Silver Syndrome click For Medical Professionals only. russell – silver syndrome,,Print this article, (Alexander Russel, 20th century, British http://www.amershamhealth.com/medcyclopaedia/Volume VII/RUSSELL SILVER SYNDROME

Medcyclopaedia About Medcyclopaedia Amersham Health Search for: Type a word or a phrase. All forms of the word are searchable. Advanced search Browse entry words starting with: A B C D ... Other characters Try our Medcyclopaedia Premium Edition with added tools and functionality tailored to make your working day easier. The following tools are presently available: Expanded search *For Medical Professionals only, registration required Russell – silver syndrome, (Alexander Russel, 20th century, British paediatrician; Henry Silver, born 1918, American paediatrician), a syndrome in which the children are of low birth weight, have short stature, frontal bossing with a pseudohydrocephalic appearance and a small triangular face. Facial or limb asymmetry are frequent. There are variable endocrine and sexual abnormalities, and mental retardation. Radiological manifestations are variable hand abnormalities; clinodactyly, Kirner deformity ivory epiphysis and syndactyly . There is skeletal asymmetry, retarded skeletal maturation with differential skeletal maturation on both sides. Multiple other dysmorphic features of the skeleton and the renal tract are reported. HC The Encyclopaedia of Medical Imaging Volume VII Welcome to Medcyclopaedia.

56. Russell-Silver Syndrome - Overview russellsilver syndrome. Alternative names Children with russell-silver syndromeappear sporadically in families with no prior history of the condition. http://www.wfubmc.edu/besthealth/ency/article/001209.htm

Disease Injury Nutrition Poison ... Prevention Russell-Silver syndrome Alternative names: Silver syndrome Definition: A condition of unknown origin, but which is characterized by extremely short stature and frequent asymmetry. Causes, incidence, and risk factors: Genetic problems are thought to play a part in this syndrome although no pattern of inheritance has been determined. Children with Russell-Silver syndrome appear sporadically in families with no prior history of the condition. Children with Russell-Silver syndrome generally achieve less than 5 feet at adult height. Side-to-side asymmetry is fairly common. This asymmetry may occur anywhere including the face. Other findings include excessive sweating , a small triangular face which makes the skull look large by comparison, inward curved the fingers, and pigmented skin lesions called cafe-au-lait spots Acquired On: 1/1/97 Acquired From: Mosby Publishing Company The information provided herein should not be used for diagnosis or treatment of any medical condition. It is provided for your general information and is not a substitute for medical care or supervised medical treatment. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. adam.com is a founding member of Hi-Ethics (http://www.hiethics.com)

57. Russell-Silver Syndrome - Treatment russellsilver syndrome. Alternative names silver syndrome. There is no specifictreatment for russell-silver syndrome. Symptoms are treated as necessary. http://www.wfubmc.edu/besthealth/ency/article/001209trt.htm

Disease Injury Nutrition Poison ... Prevention Russell-Silver syndrome Alternative names: Silver syndrome Treatment: There is no specific treatment for Russell-silver syndrome. Symptoms are treated as necessary. Sometimes growth hormone replacement is recommended, with varying results. Expectations (prognosis): As the child ages, many will improve in growth and appearance. There is a slight increase in the risk for Wilms' tumor Complications: self esteem and emotional problems related to appearance chewing or speaking difficulty if jaw is very small Calling your health care provider: There may be some indications of this condition at birth. Call your health care provider if your child does not seem to be developing or growing normally. Acquired On: 1/1/97 Acquired From: Mosby Publishing Company The information provided herein should not be used for diagnosis or treatment of any medical condition. It is provided for your general information and is not a substitute for medical care or supervised medical treatment. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. adam.com is a founding member of Hi-Ethics (http://www.hiethics.com)

58. Health Library - Russell-Silver Syndrome Search. russellsilver syndrome. Self Help Clearinghouse. russell-silversyndrome Support Network. National network. Founded http://www.stjosephhealth.org/library/healthguide/SelfHelp/topic.asp?hwid=shc29r

59. Health Library Rural Issues. russellsilver syndrome. russell-silver syndrome Support Network-russell-silversyndrome. space, Home Contact Us Site Map Privacy Policy St. http://www.stjosephhealth.org/library/healthguide/SelfHelp/_SearchResults.asp?le

60. Health Library - Russell-Silver Syndrome Your Health. Search. russellsilver syndrome. Self Help Clearinghouse.russell-silver syndrome Support Network. National network. http://yourhealth.stlukesonline.org/Library/HealthGuide/SelfHelp/topic.asp?hwid=

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