21. FDA Approves First Oral Medication For Pulmonary Arterial Hypertension Describes the trial results and subsequent approval of Tracleer. http://www.fda.gov/bbs/topics/ANSWERS/2001/ANS01121.html

FDA Talk Papers are prepared by the Press Office to guide FDA personnel in responding with consistency and accuracy to questions from the public on subjects of current interest. Talk Papers are subject to change as more information becomes available. Print Media: 301-827-6242 November 20, 2001 Broadcast Media: 301-827-3434 Consumer Inquiries: 888-INFO-FDA FDA APPROVES FIRST ORAL MEDICATION FOR PULMONARY ARTERIAL HYPERTENSION Pulmonary arterial hypertension (PAH) is defined as abnormally high blood pressure in the arteries between the heart and lungs. PAH significantly reduces the ability of patients to exert themselves physically without becoming short of breath. PAH significantly shortens the life span of patients because it leads to heart failure. Tracleer blocks the action of endothelin, a substance made by the body. Endothelin narrows blood vessels and elevates blood pressure. Although endothelin is present in healthy people, high concentrations of the hormone have been found in the plasma and lungs of patients with PAH suggesting it is capable of causing the disease. The use of Tracleer requires attention to two significant risks: liver toxicity and the drug's potential to damage a fetus. In order to ensure careful attention to monitoring for these risks, Tracleer will be available only through a direct distribution program from the drug's manufacturer, Actelion Pharmaceuticals US, Inc., of South San Francisco, Calif. It will not be available in commercial pharmacies.

22. Pulmonary Hypertension And Cor Pulmonale Articles presented at the Sunrise Seminar held Feb. 1998. http://www.int-med.uiowa.edu/TrainingPrograms/pulmonary/fellowship/Sunrise Semin

23. N C H S - FASTATS - Hypertension hypertension (All figures are for US). Percent of Americans Ages 2074 With hypertension23% (1988-94). hypertension Is Most Prevalent in the Black Population. http://www.cdc.gov/nchs/fastats/hyprtens.htm

A B C D ... I J K L M N ... P Q R S T U ... W X Y Z FASTATS Home NCHS Home Accessibility Search NCHS ... Contact us Hypertension (All figures are for U.S.) Percent of Americans Ages 20-74 With Hypertension: Hypertension Is Most Prevalent in the Black Population Over Three-Quarters of Women Aged 75 and Over Have Hypertension Sixty-four Percent of Men Aged 75 and Over Have Hypertension Source: Health, United States, 2002 Table 68 Deaths Annually: Death Rate: 8.6 deaths per 100,000 population Source: National Vital Statistics Reports, Vol.50, No. 15 Approximately 37 million were told they had heart disease Vital and Health Statistics Series 10, No. 209 In there were million Office Visits for Hypertension Source: Advance Data 328 Comprehensive Data Hypertension Prevalence Among Adults, According to Age, Race, Sex, and Hispanic Origin Health, United States 2002, Table 68 View/download PDF Number and Percent Distribution of Ambulatory Care Visits for Hypertension, by Type of Setting, 1997 View/download PDF Related Links Mortality Data National Center for Chronic Disease Prevention and Health Promotion National Heart, Lung and Blood Institute

24. The Simons Adventures Post-Transplant Our journey with Primary Pulmonary hypertension and through double lung transplant for our son. From Houston to St. Louis to Denver to LA Children's. http://thesimons.ws

Continuing in our journey. 15403 Copper Branch Houston, TX 77095 Last updated 11-12-2002 Go here for Excerpts from David Go here for Past Medical Pictures of David This page is designed specifically to help keep those interested in the progress of David's double-lung transplant updated. We will be periodically updating this site with new information. Please note that this is our own personal diary of events and not intended to be used as a guideline for anyone else who may be going through the same situation. Latest Happenings - Congratulations for accomplishments 2002 Halloween Pumpkin Carving Square Dance Performance at School David in a Race 1/4 Mile (09-29-01) What one must do after a race! Victory Metal November 2002 Happenings June 2002 Happenings March 2002 Happenings January 2002 Happenings ... November 1999 Happenings Just a brief history: David was diagnosed in 1995 at the age of 3yrs. with Primary Pulmonary Hypertension (PPH) after several concurrent illnesses. He seemed to always be sick with something. Before diagnosis, he had pneumonia at least once, bronchitis several times, colds, tubes in his ears, tonsils and adnoids removed, etc. He was diagnosed at Texas Childrens Hospital, but were told at that time that he could have 6 months left to live and to take him home and enjoy the time we had with him. PPH is a rare disorder, especially for children, and there just weren't many people that knew how to deal with the illness. After extensive research on our own, we found people who did know about the illness, none in Texas however.

25. Hypertension Diagnostics, Inc. Develops, designs, and markets a cardiovascular profiling system. Eagan, Minnesota. (Nasdaq HDII).Category Business Major Companies Publicly Traded H......Welcome! hypertension Diagnostics, Inc. welcomes you! Early assessment of vasculardisease with the CVProfilor ®. Welcome to hypertension Diagnostics, Inc. http://www.hdi-pulsewave.com/

News Events Search Contact Us ... November 16, 2002 Welcome! Hypertension Diagnostics, Inc. welcomes you! Physicians, consumers, researchers and investors will find news and information about cardiovascular health, the CVProfilor system and HDI at this site. Select from the groups below, or browse the news articles that follow: Early assessment of vascular disease with the CVProfilor Welcome to Hypertension Diagnostics, Inc. We have developed a method for non-invasively measuring the elasticity of large and small arteries, providing early assessment of vascular disease. HDI's CVProfilor allows a physician or researcher to profile individuals with respect to their cardiovascular health. This capability is incorporated into a series of products designed by HDI specifically for use in both clinics and research environments. HDI's patented profiling method is now available in several products, offered internationally and in the U.S. MORE PRODUCT INFORMATION Recent news An article from the American Heart Association: High Blood Pressure Drug Eases Vessel Stiffness, Lowers Systolic Pressures

26. HYPERTENSION (HIGH BLOOD PRESSURE) Page 4 Abstracts covering the role of various nutrients in hypertension and related diseases. http://lef.org/protocols/abstracts/abstr-060c.html

LEF Site Search All categories Protocols Health Conditions Products LE Magazine Medical Abstracts What's Hot FDA Information About LEF LEF News Research Health Concerns Funded Research Track Record Innovative Doctors ... Scientific Advisory Free Product Directory Click for a FREE copy of our Product Directory LEF Membership What is LEF? Benefits Become a Member Renewals ... Become a Subscriber Our call center has now expanded its hours Monday thru Friday: 8:30am to 12:00am EST 5:30am to 9:00pm PST Saturday hours are: 9:00am to 8:00pm EST 6:00am to 5:00pm PST Sunday hours are: 11:00am to 7:00pm EST 8:00am to 4:00pm PST If you'd like to order by phone or speak to a live person for help, just call toll free: Customer Service Info Privacy Policy We subscribe to the HONcode principles. Verify here HYPERTENSION (HIGH BLOOD PRESSURE) (Page 4) Printing? Use This! Garlic (Allium sativum) and onion (Allium cepa): a review of their relationship to cardiovascular disease Plants and hypotensive, antiatheromatous and coronarodilatating action. Muscle fibre types, ubiquinone content and exercise capacity in hypertension and effort angina. ... Prevention of preeclampsia with calcium supplementation and its relation with the L-arginine:nitric oxide pathway. Garlic (Allium sativum) and onion (Allium cepa): a review of their relationship to cardiovascular disease

27. Société Québécoise D'Hypertension Arterielle © 2002 Informations g©n©rales, et acc¨s   des pages r©serv©es, accessibles apr¨s inscription. http://www.hypertension.qc.ca/

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28. Jhh Index Page nature.com, about npg, nature science update, naturejobs, natureevents,help, Nature Publishing Group, Journal of Human hypertension. SEARCH http://www.nature.com/jhh/

nature.com about npg nature science update naturejobs ... help SEARCH my account e-alerts subscribe register ... Journal home For readers Content Online sample issue E-alerts Indexed in ... Society publishing NPG Subject areas Access material from all our publications in your subject area: Biotechnology Cancer Chemistry Clinical Medicine ... Physics ISSN 0950-9240 2003 Volume 17 Publishes 12 issues a year ISI 2001 Impact Factor 1.689 Rank 25/50 Peripheral vascular disease View tables of contents Essential reading for all clinicians who deal with hypertensive patients. Audience Practising cardiologists, general practitioners, obstetricians, nephrologists, research workers, nurses and epidemiologists.

29. Management Of Chronic Hypertension During Pregnancy Summary, Redirect Article discussing treatment, possible complications, and monitoring techniques. http://www.ahcpr.gov/clinic/pregsum.htm

The summary of Evidence Report/Technology Assessment: Number 14: Management of Chronic Hypertension During Pregnancy has been moved. It is now at: http://www.ahrq.gov/clinic/epcsums/pregsum.htm Please update your bookmarks. AHRQ Home Page

30. Kidney Disease On Medbroadcast.com General kidney information, disease treatment and prevention. Covers related topics of diabetes, hypertension and nutrition. http://www.medbroadcast.com/health_topics/health_conditions/kidney/index.shtml

Diet, renal transplants, dialysis, and steroids can all be used to treat kidney disease. But how do you know if you have a kidney infection or kidney disease - what are the signs and symptoms? And why is kidney disease potentially life threatening? Find out right here on the Kidney Channel, with illustrations and information on causes, diagnoses and treatments. Keep track of your health and medical information including: Healthcare Providers Diabetic Records Blood Pressure Hospitalization History Medical History Medicine Cabinet Go to My Health Record or look at a sample record Useful health management tools: What do you know about your kidneys? See A - Z of all tools See A - Z of all videos and animations Find out more about Find out about clinical trials of new drugs. Trials where you live, or every trial underway. About clinical trials Find clinical trials Useful support organizations: Kidney Foundation of Canada National Kidney Foundation - USA Find all other support groups Find a Canadian physician Find a US physician MEDLINE ... Dictionary Kidney General information How do kidneys work?

31. Canadian Hypertension Society Website The release of the CHS 2002 recommendations on hypertension will be postponeduntil they have been updated in light of ALLHAT results La diffusion des http://www.chs.md/

C ome in and stay a while... E ntrez et bonne visite...

32. Metabolic Syndrome A continuing medical education monograph on the Metabolic Syndrome, otherwise known as insulin resistance or syndrome X. http://www.metabolicsyndromeonline.com

OPTIMAL MANAGEMENT OF HYPERTENSION AND OBESITY IN THE Metabolic Syndrome CME MONOGRAPH CME Monograph Click here to view. This monograph is presented in PDF format. If you do not have Adobe Acrobat Reader® installed, please click here to install Acrobat Reader 4.0. Guest Editor Target Audience Goals Accreditation ... Support Guest Editor: George Bakris, MD ACCESS Medical Group Department of Continuing Medical Education 3395 N. Arlington Heights Road, Suite A Arlington Heights, IL 60004-1566

33. NHLBI, JNC VI Report As an update, it provides a contemporary approach to hypertension preventionand control. New information since JNC V includes data http://www.nhlbi.nih.gov/guidelines/hypertension/jncintro.htm

The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure You may obtain the document in following ways: View online (in formats below) [PDF document, 546 K, need Acrobat Reader to review] Information for visitors using screen readers Information about PDF Printed Copies Order online Order by telephone, fax, or mail Price Information Single copy 25 copies 100 copies NHLBI Home Page Clinical Guidelines High Blood Pressure Information for Professionals Please send us your feedback, comments, and questions by using the appropriate link on the page, Contact the NHLBI Note to users of screen readers and other assistive technologies: please report your problems here.

34. P: Pediatrics: Nephrology: Hypertension Information about high blood pressure in children and teenagers. From the Children's Hospital at Montefiore, Bronx, New York. http://www.montefiore.org/prof/clinical/ped/progserv/nephrology/hypertension/ind

35. NHLBI, Primary Pulmonary Hypertension National Institute of Health pamphlet covering the incidence, symptoms, cause, diagnosis, and treatment Category Health Conditions and Diseases hypertension Pulmonary......Image of the cover Primary Pulmonary hypertension. Answers your questionsabout unexplained elevated blood pressure in the pulmonary artery. http://www.nhlbi.nih.gov/health/public/lung/other/pph.htm

Primary Pulmonary Hypertension Answers your questions about unexplained elevated blood pressure in the pulmonary artery. This booklet covers the incidence, symptoms, cause, diagnosis, and treatment of the disease. Much of what is known about primary pulmonary hypertension (PPH) stems from the research on patients involved in the Primary Pulmonary Hypertension Patient Registry. Findings from this study as well as information on plans for future research are presented. Practical suggestions are given for patients living with PPH. A resource section and glossary are included. NIH Publication No. 96-3291. 21 pages. You may obtain the document in the following ways: View online (in formats below) [Web (HTML) document] [PDF document, 195 K, need Acrobat Reader to review] Information for visitors using screen readers Information about PDF Printed Copies Order online Order by telephone, fax, or mail Price Information Single copy 25 copies 100 copies Home Page Lung Information for the General Public Please send us your feedback, comments, and questions

36. Hypertension Online IN THE SLIDE LIBRARY! The Relationship of hypertension Treatment to CVDRisk Reduction. hypertension Detection and Followup Program - NEW! http://www.hypertensiononline.org/

Designed for the health care professional, Hypertension Online gives you direct access to the most current, reliable information in the field of hypertension, including breakthrough research, clinical trials , guidelines, risk factors, and emerging concepts. Includes a PowerPoint slide library . For a complete list of slide talks, vist our slide library Menu1=new Array("Home","http://www.hypertensiononline.org/index.cfm","",6,20,147,"#8A0101","#5C0000","white","white","#5C0000"); Menu1_1=new Array("Welcome","http://www.hypertensiononline.org/index.cfm","",0,18,184,"#5A5A5A","#999999","white","","#666666"); Menu1_2=new Array("About This Site","http://www.hypertensiononline.org/home/about_HOL.cfm","",0,18,184,"#5A5A5A","#999999","white","","#666666"); Menu1_3=new Array("Editorial Board","http://www.hypertensiononline.org/home/editorial.cfm","",0,18,184,"#5A5A5A","#999999","white","","#666666"); Menu1_4=new Array("Register for Updates","http://www.hypertensiononline.org/home/register.cfm","",0,18,184,"#5A5A5A","#999999","white","","#666666"); Menu1_5=new Array("Suggestion Box","http://www.hypertensiononline.org/home/suggestions.cfm","",0,18,184,"#5A5A5A","#999999","white","","#666666");

37. Lippincott Williams & Wilkins - Current Opinion In Nephrology And Hypertension Similar pages Cardiovascular Disease Centre for Chronic Prevention and public health approach. hypertension. hypertension, also known ashigh blood pressure, is widely prevalent in Canada. What makes http://www.co-nephrolhypertens.com/

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38. Intracranial Hypertension Research Foundation The Intracranial hypertension Research Foundation is a Nonprofit Organization that was formed to sponsor the development of new research to determine why IH happens, and how new therapies might better manage the disorder while seeking a cure. Sign up for our newsletter and the latest updates regarding diagnosis and treatment of IH. http://www.ihrfoundation.org

Welcome to the Intracranial Hypertension Research Foundation site. We are here to help Intracranial Hypertension (IH) is the general name for the disorders in which the cerebro-spinal fluid (CSF) pressure within the skull is too high. (Intracranial means inside of the skull . Hypertension refers to high fluid pressure . Old names for IH include Benign Intracranial Hypertension and Pseudotumor Cerebri). The Intracranial Hypertension Research Foundation (IHRF) funds and supports medical research to develop better therapies to control Intracranial Hypertension (IH) while ultimately seeking a cure for IH. The Foundation also provides support, education, and encouragement for IH patients , their families , and medical professionals We are the only non-profit organization in the world devoted to supporting research to find a cure for IH Latest News: Read the latest news about IH and the Foundation.

39. Hypertension Diagnostics, Inc. Develops, designs, and markets a cardiovascular profiling system. Eagan, Minnesota. (Nasdaq HDII). http://www.HDI-PULSEWAVE.COM/

News Events Search Contact Us ... November 16, 2002 Welcome! Hypertension Diagnostics, Inc. welcomes you! Physicians, consumers, researchers and investors will find news and information about cardiovascular health, the CVProfilor system and HDI at this site. Select from the groups below, or browse the news articles that follow: Early assessment of vascular disease with the CVProfilor Welcome to Hypertension Diagnostics, Inc. We have developed a method for non-invasively measuring the elasticity of large and small arteries, providing early assessment of vascular disease. HDI's CVProfilor allows a physician or researcher to profile individuals with respect to their cardiovascular health. This capability is incorporated into a series of products designed by HDI specifically for use in both clinics and research environments. HDI's patented profiling method is now available in several products, offered internationally and in the U.S. MORE PRODUCT INFORMATION Recent news An article from the American Heart Association: High Blood Pressure Drug Eases Vessel Stiffness, Lowers Systolic Pressures

40. PHCentral - Pulmonary Hypertension: The Complete Resource Features medical information, support options, news, events, research, forums and mailing lists, legislat Category Health Conditions and Diseases hypertension Pulmonary......The PHCentral Mission To be the definitive internet resource for Pulmonary hypertensionrelated information for Patients, Caregivers and Medical Professionals http://www.phcentral.org/

Help Advanced Search Site Map About PHC The PHCentral Mission: To be the definitive internet resource for Pulmonary Hypertension related information for Patients, Caregivers and Medical Professionals. What's New the Week of 3/24/03: Newsroom: 3-27 Treating Sleep Apnea Helps Heart Failure Current Feature: A Life on the Move Reception Room We invite you to visit the PHCentral Reception Room, where you can make inquiries, ask for help and learn about our organization. You may post as a guest, or register and fill out a profile. Unlike our Web Board, which is designed for PH patients and caregivers, this forum is open to any and all. So, if you are a friend of a person with PH or just want to find out more about the disease for your own reasons, we're here to help you. You'll find profiles of PHC staff members who will assist you. Since their profile includes a little recap of their own PH experience, you should have no difficulty in finding someone to help you with your

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